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Pragmatic trials are trials designed to inform real-world clinical practice. They are often characterized by their focus on practical aspects of design which include the recruitment and consent process, as well as adherence and the use of standard equipment.
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Pragmatic Software, a software firm offers a range of casino games for online gambling platforms. Pragmatic's iGaming software is used by leading operators as well as casinos that are located in the land. The company offers front-end design tools, analysis, marketing, promotions, payment systems, security, customer service, and bug reporting. Additionally, the company provides its players a secure environment that features high-quality graphics and games.
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Gates of Olympus, a new game by the company, transports players into the realm of the ancient Greek Gods where Zeus is the one who oversees all the action. This high-volatility slot game comes with a Pay Anywhere feature that awards players with winnings when they get eight or more identical symbols anywhere on the reels. It also has an extremely lucrative Free Spins feature with multipliers that can reach up to 500x bet.
A pragmatic study that involves a variety investigators and includes participants from different geographical areas is the Home Blood Pressure Management study (HBPM). This kind of heterogeneity, that is crucial for a pragmatic trial to be reliable and to reduce bias in the results, is also necessary. However excessive heterogeneity could cause issues with the design of the trial.
Pragmatic Play, a major player on the live casino market offers a variety of classic table games such as Blackjack and Roulette. The company's live studios in Romania and Malta offer a real-life gaming experience for its customers, as well as an extensive selection of virtual betting options. The company also has created various interactive games to make gambling online enjoyable. Some of these shows are broadcast live and some include famous people from the field.
Mobile compatibility
Pragmatic Play is a relatively new player in the online casino market however, it has already earned a name with its mobile-friendly slots. Their games are optimized for mobile devices, and run on HTML5 technology. They are also licensed and regulated by respected gaming authorities, which ensure fairness and transparency. This is a great indication for players as it implies that the games are checked and verified to ensure that the outcomes of each round are random and fair.
Pragmatic Play offers not only mobile-friendly slot machines, but also tables games and live casinos. The company is licensed and regulated by several governing bodies, including the Malta Gaming Authority and UK Gambling Commission. The games of the company are protected by high-end encryption, and its security team is on hand to assist players in any situation.
Pragmatic Play's slot games are popular for both newbies as well as seasoned players. They have modern graphics and traditional themes. They offer a variety of paylines and bonus rounds and a majority of them have progressive jackpots. They are also not very volatile and you can expect to enjoy a long playing session with them.
Most Pragmatic Play games are available for free, which means you can test them before deciding to play them with real money. These free games can be played on any device including laptops, desktops and smartphones. They are easy to navigate, and you can play from anywhere with an internet connection. Some Pragmatic Play websites even let you test your luck while moving around by playing a test mode. This lets you familiarize yourself with game rules and features before playing for real money.
Legality
Pragmatic Play has earned a reputation for providing high-quality games and a superior user experience. Its software can be used on mobile devices as well as in various languages. It has been recognized as one of the most popular gaming platforms in the casino industry despite its relative youth. The most recent releases include Wolves 5 reel video slot that has a healthy RTP and stunning graphics. Other notable titles include Wolf Gold and Chilli Heat.
Pragmatic trials aim to mimic real-life situations and attain maximum external validity. They are usually commissioned by policy makers and practitioners to guide their decision-making. They are also a good way to identify the causal relationship between an intervention and its results. However, they should not be used in lieu for explanation trials.
The pragmatism idea is controversial, and there are questions about whether pragmatic trials should replace explanatory tests or if they should be a complement to them. Schwartz and Lellouch1 suggested a distinction between explanatory studies, which confirm the physiological hypothesis or clinical hypothesis, and pragmatic trials, which inform the decision-making process for policy and practice. They also proposed a framework called PRECIS for pragmatic trials.2 This tool attempted to define the elements of a pragmatic research study, including recruitment, design, delivery of the intervention and follow-up.
There is a growing trend in the number of pragmatic trials published. A recent Medline search using the keywords pragmatic and naturalistic, restricted to randomized controlled trials (RCTs) resulted in 34 articles, which are shown in red in Figure 2. This is a sign that the health sciences community is becoming more sensitive to the issue of pragmatism. It is important to note that the majority of these studies were conducted in primary-care settings.